Description

Spironolactone (25 mg. | 28 tabs.)

The active ingredient of the tablets is Spironolactone. Spironolactone belongs to a particular group of medicines, known as aldosterone antagonists, which inhibit the action of the hormone aldosterone. One of the functions of aldosterone is to ensure that the body retains sodium. It forms part of a system that regulates the balance of fluids and salts in the body (‘RAAS’, renin angiotensin aldosterone system). Spironolactone promotes the excretion of urine in patients in whom there is an accumulation of fluid in the tissues (oedema) or in the abdominal cavity (ascites) by increasing the amount of sodium (salt) excreted in the urine. Potassium loss as a possible consequence of using certain diuretics is reduced. The antihypertensive effect relies on the excretion of water and salt. Spironolactone film-coated tablets may be prescribed by your doctor for the treatment of:

• Accumulation of fluid in the tissues as a result of heart disorders;
• Severe heart failure (NYHA III-IV);
• Raised blood pressure as an adjunct to a salt-free diet and diuretics;
• Certain kidney disorders;
• Accumulation of fluid in the tissues in the abdominal cavity.

Spironolactone film-coated tablets may also be used: during medical investigations (diagnostics) to confirm the presence of disorders in which too high a level of aldosterone is produced in the adrenal cortex (known as Conn’s disease) and treatment. Children should only be treated under guidance of a paediatric specialist.